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SARS-CoV-2 S1 Protein
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Catalogue No: abx160074
Price:
US$3,480.00
(Size: 1 mg)
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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike S1 Protein is a recombinant protein expressed in Insect cells. The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
Research Articles on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) S1 Protein
| Target | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) S1 Protein |
| Origin | Virus |
| Expression | Recombinant |
| Tested Applications | ELISA, WB |
| Host | Insect |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Form | Liquid |
| Purity | ≥ 85% (SDS-PAGE) |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight | Calculated MW: 76 kDa Observed MW (12% reducing SDS-PAGE): 85 kDa. Difference is due to glycosylation. |
| Sequence | The amino acid sequence is proprietary. |
| Tag | His tag |
| Buffer | PBS, pH 7.4. Does not contain preservatives. |
| Availability | Shipped within 10-20 working days. |
| Note | This product is for research use only. This product is shipped with dry ice. |
| Directions for use | Centrifuge before opening to ensure complete recovery of vial contents. |