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SARS-CoV-2 Spike Glycoprotein Antibody
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Catalogue No: abx376479
Price:
US$348.00
(Size: 50 µg)
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SARS-CoV-2/COVID-19 Spike Glycoprotein Antibody is a chimaeric recombinant antibody expressed in CHO cells against SARS-CoV-2 Spike Glycoprotein, containing Mouse variable region and Human IgM constant region. The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
Research Articles on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Glycoprotein
| Target | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Glycoprotein |
| Clonality | Monoclonal |
| Reactivity | Virus |
| Origin | Human |
| Expression | Recombinant |
| Tested Applications | ELISA, WB |
| Host | Human, Mouse |
| Recommended dilutions | ELISA: 1/5000 - 1/10,000, WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant SARS-CoV-2 S protein. |
| Isotype | IgM |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Buffer | PBS, pH 7.5. |
| Concentration | 1.0 mg/ml |
| Availability | Shipped within 10-20 working days. |
| Note | This product is for research use only. |