SARS-CoV-2 Spike Glycoprotein Antibody

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Catalogue No: abx376479
Price: US$348.00
(Size: 50 µg)

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Datasheet SDS
SARS-CoV-2/COVID-19 Spike Glycoprotein Antibody is a chimaeric recombinant antibody expressed in CHO cells against SARS-CoV-2 Spike Glycoprotein, containing Mouse variable region and Human IgM constant region.

The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.

Target Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Glycoprotein
Clonality Monoclonal
Reactivity Virus
Origin Human
Expression Recombinant
Tested Applications ELISA, WB
Host Human, Mouse
Recommended dilutions ELISA: 1/5000 - 1/10,000, WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant SARS-CoV-2 S protein.
Isotype IgM
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Buffer PBS, pH 7.5.
Concentration 1.0 mg/ml
Availability Shipped within 10-20 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Glycoprotein