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SARS-CoV-2 Spike Protein Antibody
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Catalogue No: abx229483
Price:
US$406.00
(Size: 50 µl)
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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike Protein Antibody is a chimaeric recombinant Monoclonal Antibody against SARS-CoV-2/COVID-19 S Protein, containing Mouse variable region and Human IgG1 constant region. The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
Research Articles on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Trimeric Spike 1 Protein
| Target | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Trimeric Spike 1 Protein |
| Clonality | Monoclonal |
| Clone | C611 |
| Reactivity | Virus |
| Origin | Human |
| Expression | Recombinant |
| Tested Applications | ELISA |
| Host | Human, Mouse |
| Recommended dilutions | ELISA: 1/5000 - 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant SARS-CoV-2 Spike RBD Protein |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | 0.2 µm filtered. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Buffer | PBS. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
| Directions for use | Centrifuge before opening to ensure complete recovery of vial contents. |