SARS-CoV Nucleoprotein Antibody

SARS-CoV Nucleoprotein Antibody is a Rabbit Polyclonal antibody for the detection of SARS-CoV Nucleoprotein.

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

Target	SARS-CoV
Clonality	Polyclonal
Reactivity	Virus
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	ELISA: 1/5000 - 1/10000, WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant SARS-CoV Nucleoprotein/NP Protein
Isotype	IgG
Form	Liquid
Purification	Purified by antigen affinity chromatography. 0.2 µm filtered.
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Buffer	PBS.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.
Directions for use	Centrifuge before opening to ensure complete recovery of vial contents.

Research Articles on SARS-CoV

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