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SARS-CoV Nucleoprotein Antibody
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Catalogue No: abx201412
Price:
US$406.00
(Size: 50 µl)
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SARS-CoV Nucleoprotein Antibody is a Mouse Monoclonal antibody for the detection of SARS-CoV Nucleoprotein. Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Research Articles on SARS-CoV
| Target | SARS-CoV |
| Clonality | Monoclonal |
| Reactivity | Virus |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/5000 - 1/10000, WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant SARS-CoV Nucleoprotein/NP Protein |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified by Protein A affinity chromatography. 0.2 µm filtered. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Buffer | PBS. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
| Directions for use | Centrifuge before opening to ensure complete recovery of vial contents. |