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Sterol Regulatory Element-Binding Protein Cleavage-Activating Protein (SCAP) Antibody
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Catalogue No: abx034001
Price:
US$326.25
(Size: 80 µl)
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SCAP is a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
Research Articles on Sterol Regulatory Element-Binding Protein Cleavage-Activating Protein (SCAP)
| Target | Sterol Regulatory Element-Binding Protein Cleavage-Activating Protein (SCAP) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/100, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 604-632 amino acids from the Central region of human SCAP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q12770 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8N2E0, Q8WUA1 |
| UniProt Entry Name | SCAP_HUMAN |
| NCBI Accession | NP_036367.2 |
| KEGG | hsa:22937 |
| String | 9606.ENSP00000265565 |
| Molecular Weight | Calculated MW: 140 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow and Pig SCAP. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |