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Scavenger Receptor Class B Member 1 (SCARB1) Antibody
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Catalogue No: abx031121
Price:
US$326.25
(Size: 80 µl)
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Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester (By similarity).
Research Articles on Scavenger Receptor Class B Member 1 (SCARB1)
| Target | Scavenger Receptor Class B Member 1 (SCARB1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of human SCARB1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8WTV0 (UniProt, ExPASy) |
| UniProt Secondary AC | F8W8N0, Q14016, Q52LZ5, Q6KFX4 |
| UniProt Entry Name | SCRB1_HUMAN |
| Gene Symbol | SCARB1 |
| KEGG | hsa:949 |
| String | 9606.ENSP00000261693 |
| Molecular Weight | Calculated MW: 60.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Pig SCARB1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |