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Lysosome Membrane Protein 2 (SCARB2) Antibody
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Catalogue No: abx004803
Price:
US$348.00
(Size: 60 µl)
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SCARB2 Antibody is a Rabbit Polyclonal antibody against SCARB2. The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Lysosome Membrane Protein 2 (SCARB2)
| Target | Lysosome Membrane Protein 2 (SCARB2) |
| Clonality | Polyclonal |
| Reactivity | Rat |
| Tested Applications | IHC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human SCARB2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14108 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DKD8, E7EM68, Q53Y63 |
| UniProt Entry Name | SCRB2_HUMAN |
| Gene Symbol | SCARB2 |
| GeneID | 950 |
| NCBI Accession | NP_005497.1 |
| KEGG | hsa:950 |
| String | 9606.ENSP00000264896 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
