Lysosome Membrane Protein 2 (SCARB2) Antibody

SCARB2 Antibody is a Rabbit Polyclonal antibody against SCARB2. The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target	Lysosome Membrane Protein 2 (SCARB2)
Clonality	Polyclonal
Reactivity	Rat
Tested Applications	ELISA
Host	Rabbit
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 28-298 of human SR-B2/LIMPII.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14108 (UniProt, ExPASy)
UniProt Secondary AC	B4DKD8, E7EM68, Q53Y63
UniProt Entry Name	SCRB2_HUMAN
Gene Symbol	SCARB2
GeneID	950
NCBI Accession	NP_005497.1
KEGG	hsa:950
String	9606.ENSP00000264896
Molecular Weight	Calculated MW: 54 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Lysosome Membrane Protein 2 (SCARB2)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue