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Sodium Voltage-Gated Channel Alpha Subunit 5 (SCN5A) Antibody
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Catalogue No: abx030654
Price:
US$290.00
(Size: 80 µl)
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The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms.
Research Articles on Sodium Voltage-Gated Channel Alpha Subunit 5 (SCN5A)
| Target | Sodium Voltage-Gated Channel Alpha Subunit 5 (SCN5A) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human SCN5A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14524 (UniProt, ExPASy) |
| UniProt Entry Name | SCN5A_HUMAN |
| KEGG | hsa:6331 |
| String | 9606.ENSP00000410257 |
| Molecular Weight | Calculated MW: 227 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat SCN5A. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |