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Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A) Antibody
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Catalogue No: abx004240
Price:
US$217.50
(Size: 20 µl)
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SCNN1A Antibody is a Rabbit Polyclonal antibody against SCNN1A. Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Research Articles on Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A)
| Target | Amiloride Sensitive Sodium Channel Subunit Alpha (SCNN1A) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 105-225 of human SCNN1A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P23458 (UniProt, ExPASy) |
| UniProt Secondary AC | Q59GQ2, Q9UD26 |
| UniProt Entry Name | JAK1_HUMAN |
| Gene Symbol | JAK1 |
| GeneID | 6337 |
| NCBI Accession | NP_001029.1 |
| KEGG | hsa:3716 |
| String | 9606.ENSP00000343204 |
| Molecular Weight | Calculated MW: 76 kDa Observed MW: 75 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |