Succinate Dehydrogenase Complex Subunit B (SDHB) Antibody

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Catalogue No: abx031320
Price: US$326.25
(Size: 80 µl)
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Succinate Dehydrogenase Complex Subunit B (SDHB) Antibody
Succinate Dehydrogenase Complex Subunit B (SDHB) Antibody

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Datasheet SDS
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Target Succinate Dehydrogenase Complex Subunit B (SDHB)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 205-234 amino acids from the C-terminal region of human SDHB.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P21912 (UniProt, ExPASy)
UniProt Secondary AC B2R545, Q0QEY7, Q9NQ12
UniProt Entry Name SDHB_HUMAN
Gene Symbol SDHB
KEGG hsa:6390
String 9606.ENSP00000364649
Molecular Weight Calculated MW: 31.6 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse, Cow and Pig SDHB.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Succinate Dehydrogenase Complex Subunit B (SDHB)
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