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Succinate Dehydrogenase Complex Subunit D (SDHD) Antibody
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Catalogue No: abx026621
Price:
US$326.25
(Size: 80 µl)
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Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma.
Research Articles on Succinate Dehydrogenase Complex Subunit D (SDHD)
| Target | Succinate Dehydrogenase Complex Subunit D (SDHD) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SDHD. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O14521 (UniProt, ExPASy) |
| UniProt Secondary AC | A6ND90, B3KQQ8, E9PIC0, E9PIG3, E9PQI9, Q53XW5, Q6IRW2 |
| UniProt Entry Name | DHSD_HUMAN |
| Gene Symbol | SDHD |
| KEGG | hsa:6392 |
| String | 9606.ENSP00000364699 |
| Molecular Weight | Calculated MW: 17 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |