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Selenocysteine Insertion Sequence-Binding Protein 2 (SECISBP2) Antibody
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Catalogue No: abx005167
Price:
US$203.00
(Size: 20 µl)
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SECISBP2 Antibody is a Rabbit Polyclonal antibody against SECISBP2. The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.
Research Articles on Selenocysteine Insertion Sequence-Binding Protein 2 (SECISBP2)
| Target | Selenocysteine Insertion Sequence-Binding Protein 2 (SECISBP2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 585-854 of human SECISBP2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96T21 (UniProt, ExPASy) |
| UniProt Secondary AC | F8W892, Q5HYY1, Q7L1Z0, Q8IYC0, Q9H0A1 |
| UniProt Entry Name | SEBP2_HUMAN |
| Gene Symbol | SECISBP2 |
| GeneID | 79048 |
| NCBI Accession | NP_076982.3 |
| KEGG | hsa:79048 |
| String | 9606.ENSP00000364965 |
| Molecular Weight | Calculated MW: 95 kDa Observed MW: 110 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |