Segment Polarity Protein Dishevelled Homolog DVL-1 (DVL1) Antibody

Segment Polarity Protein Dishevelled Homolog DVL-1 (DVL1) Antibody is a Rabbit Polyclonal antibody for the detection of DVL1.

DVL1 is one of three DVL homologous proteins (DVL1–3) widely expressed in embryonic development and in the adult central nervous system. Dishevelled proteins are a necessary component of the Wnt and planar cell polarity developmental signaling pathways. Overexpression of DVL1 has been linked to prostate and breast cancers through the Wnt signaling pathway.

Target	Segment Polarity Protein Dishevelled Homolog DVL-1 (DVL1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	dishevelled, dsh homolog 1
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	O14640 (UniProt, ExPASy)
UniProt Secondary AC	Q5TA33, Q5TA35
UniProt Entry Name	DVL1_HUMAN
Gene Symbol	DVL1
GeneID	1855
OMIM	601365
HGNC	3084
KEGG	hsa:1855
Ensembl	ENSG00000107404
String	9606.ENSP00000368169
Molecular Weight	Observed MW: 70 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Segment Polarity Protein Dishevelled Homolog DVL-1 (DVL1)

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