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Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Antibody
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Catalogue No: abx011158
Price:
US$406.00
(Size: 100 µg)
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Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Antibody is a Rabbit Polyclonal antibody for the detection of MAP2K4. This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
Research Articles on Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4)
| Target | Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/500, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | MAP2K4 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P45985 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R7N7, B3KYB2, D3DTS5, Q5U0B8, Q6FHX4, Q6P9H2, Q6PIE6 |
| UniProt Entry Name | MP2K4_HUMAN |
| Gene Symbol | MAP2K4 |
| GeneID | 6416 |
| OMIM | 601335 |
| HGNC | 6844 |
| KEGG | hsa:6416 |
| Ensembl | ENSG00000065559 |
| String | 9606.ENSP00000410402 |
| Molecular Weight | Observed MW: 44 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |