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L-Selectin / CD62L (SELL) Antibody
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Catalogue No: abx219084
Price:
US$406.00
(Size: 100 µg)
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L-Selectin / CD62L (SELL) Antibody is a Rabbit Polyclonal antibody for the detection of L-Selectin. This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.
Research Articles on L-Selectin / CD62L (SELL)
| Target | L-Selectin / CD62L (SELL) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | L-selectin |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P14151 (UniProt, ExPASy) |
| UniProt Secondary AC | A0A024R8Z0, B2R6Q8, P15023, Q9UJ43 |
| Gene Symbol | SELL |
| GeneID | 6402 |
| OMIM | 153240 |
| HGNC | 10720 |
| Ensembl | ENSG00000188404 |
| Molecular Weight | Observed MW: 74 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |