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Semaphorin 3A (SEMA3A) Antibody
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Catalogue No: abx033665
Price:
US$326.25
(Size: 80 µl)
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SEMA3A is a member of the semaphorin family with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
Research Articles on Semaphorin 3A (SEMA3A)
| Target | Semaphorin 3A (SEMA3A) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 535-566 amino acids from the Central region of human SEMA3A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14563 (UniProt, ExPASy) |
| UniProt Entry Name | SEM3A_HUMAN |
| KEGG | hsa:10371 |
| String | 9606.ENSP00000265362 |
| Molecular Weight | Calculated MW: 88.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Chicken SEMA3A. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |