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Semaphorin 6A (SEMA6A) Antibody
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Catalogue No: abx031679
Price:
US$326.25
(Size: 80 µl)
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SEMA6A belongs to a subfamily characterized by an extracellular semaphorin domain, a transmembrane domain, and a long cytoplasmic tail. Members of this class can repel sympathetic and dorsal root ganglion axons in vitro, consistent with a traditional role as guidance signals. However, the length of the cytoplasmic tail, which includes an EVL-binding site in SEMA6A and an Src-binding site in SEMA6B, suggests that these semaphorins may also function as receptors. SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection. SEMA6A directly links the Ena/VASP and the semaphorin protein families since the SEMA6A protein is capable of selective binding to the protein EVL (Ena/VASP-like protein).
Research Articles on Semaphorin 6A (SEMA6A)
| Target | Semaphorin 6A (SEMA6A) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human SEMA6A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9H2E6 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9P2H9 |
| UniProt Entry Name | SEM6A_HUMAN |
| Gene Symbol | SEMA6A |
| String | 9606.ENSP00000257414 |
| Molecular Weight | Calculated MW: 114 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse SEMA6A. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |