Semaphorin 7A (SEMA7A) Antibody

Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.

Target	Semaphorin 7A (SEMA7A)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 178-202 amino acids from the N-terminal region of human SEMA7A.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O75326 (UniProt, ExPASy)
UniProt Secondary AC	B4DDP7, F5H1S0, Q1XE81, Q1XE82, Q1XE83, Q1XE84, Q3MIY5
UniProt Entry Name	SEM7A_HUMAN
Gene Symbol	SEMA7A
NCBI Accession	NP_001139501.1 NP_001139502.1 NP_003603.1
KEGG	hsa:8482
String	9606.ENSP00000261918
Molecular Weight	Calculated MW: 74.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Semaphorin 7A (SEMA7A)

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