Selenoprotein P / SEPP1 (SELENOP) Antibody

This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene.

Target	Selenoprotein P / SEPP1 (SELENOP)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/2000, FCM: 1/25. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 233-262 amino acids from the Central region of Human SEPP1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Store at 2-8°C for up to 2 weeks, or for longer-term, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P49908 (UniProt, ExPASy)
UniProt Secondary AC	Q6PD59, Q6PI43, Q6PI87, Q6PJF9
UniProt Entry Name	SEPP1_HUMAN
Gene Symbol	SELENOP
GeneID	6414
OMIM	601484
NCBI Accession	NP_001078955.1 NP_005401.3
KEGG	hsa:6414
String	9606.ENSP00000420939
Molecular Weight	Calculated MW: 43 kDa
Buffer	PBS containing 0.09% sodium azide.
Concentration	0.4 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Selenoprotein P / SEPP1 (SELENOP)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue