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O-Phosphoseryl-tRNA(Sec) Selenium Transferase (SEPSECS) Antibody
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Catalogue No: abx030266
Price:
US$326.25
(Size: 80 µl)
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The 21st amino acid, selenocysteine (sec), is distinct from other amino acids because it lacks its own tRNA synthetase and is the only amino acid synthesized on its cognate tRNA. Synthesis of sec begins with acylation of tRNA (sec) (TRSP; MIM 165060) by seryl-tRNA synthetase (SARS; MIM 607529) to give ser-tRNA (sec), which is subsequently phosphorylated by O-phosphoseryl-tRNA kinase (PSTK; MIM 611310) to give O-phosphoseryl-tRNA (sec). SEPSECS catalyzes the final step of sec synthesis by converting O-phosphoseryl-tRNA (sec) to selenocysteinyl-tRNA (sec) using selenophosphate as the selenium donor (Palioura et al., 2009 [PubMed 19608919]).
Research Articles on O-Phosphoseryl-tRNA(Sec) Selenium Transferase (SEPSECS)
| Target | O-Phosphoseryl-tRNA(Sec) Selenium Transferase (SEPSECS) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 444-474 amino acids from the C-terminal region of human SEPSECS. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9HD40 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K8W1, Q0D2P3, Q17RT1, Q9NXZ5, Q9UGM9, Q9Y353 |
| UniProt Entry Name | SPCS_HUMAN |
| Gene Symbol | SEPSECS |
| String | 9606.ENSP00000371535 |
| Molecular Weight | Calculated MW: 55.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |