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Septin 2 (SEPTIN2) Antibody
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Catalogue No: abx029046
Price:
US$326.25
(Size: 80 µl)
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Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
Research Articles on Septin 2 (SEPTIN2)
| Target | Septin 2 (SEPTIN2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 280-309 amino acids from the C-terminal region of human SEPT2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15019 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DGE8, Q14132, Q53QU3, Q8IUK9, Q96CB0 |
| UniProt Entry Name | SEPT2_HUMAN |
| KEGG | hsa:4735 |
| String | 9606.ENSP00000479861 |
| Molecular Weight | Calculated MW: 41.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Cow SEPTIN2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |