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Septin 7 (SEPTIN7) Antibody
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Catalogue No: abx002732
Price:
US$203.00
(Size: 20 µl)
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SEPT7 Antibody is a Rabbit Polyclonal antibody against SEPT7. This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.
Research Articles on Septin 7 (SEPTIN7)
| Target | Septin 7 (SEPTIN7) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 307-436 of human Septin 7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q16181 (UniProt, ExPASy) |
| UniProt Secondary AC | Q52M76, Q6NX50 |
| UniProt Entry Name | SEPT7_HUMAN |
| Gene Symbol | SEPTIN7 |
| GeneID | 989 |
| NCBI Accession | NP_001011553.2 |
| KEGG | hsa:989 |
| String | 9606.ENSP00000381992 |
| Molecular Weight | Calculated MW: 51 kDa Observed MW: 51 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |