Sequestosome 1 (SQSTM1) Antibody

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Catalogue No: abx239900
Price: US$406.00
(Size: 100 µg)
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WB analysis of HEK-293 cells, using SQSTM1 antibody (1/2000 dilution).
Sequestosome 1 (SQSTM1) Antibody Sequestosome 1 (SQSTM1) Antibody

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Datasheet SDS
Sequestosome-1 (P62/SQSTM1) Antibody is a Mouse Monoclonal antibody for the detection of P62/SQSTM1.

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Target Sequestosome 1 (SQSTM1)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, IF/ICC
Host Mouse
Recommended dilutions WB: 1/1000 - 1/4000, IHC: 1/50 - 1/500, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen sequestosome 1
Isotype IgG2a
Form Liquid
Purity ≥ 95% (SDS-PAGE)
Purification Purified by Protein A and Protein G affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity 12 months.
UniProt Primary AC Q13501 (UniProt, ExPASy)
UniProt Secondary AC A6NFN7, B2R661, B3KUW5, Q13446, Q9BUV7, Q9BVS6, Q9UEU1
UniProt Entry Name SQSTM_HUMAN
Gene Symbol SQSTM1
GeneID 8878
OMIM 167250
HGNC 11280
KEGG hsa:8878
Ensembl ENSG00000161011
String 9606.ENSP00000374455
Molecular Weight Observed MW: 62 kDa
Buffer PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration 2 mg/ml
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Sequestosome 1 (SQSTM1)
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