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Antithrombin-III (SERPINC1) Antibody
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Catalogue No: abx025422
Price:
US$601.75
(Size: 100 µl)
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The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. This antibody is supplied as crude ascites.
Research Articles on Antithrombin-III (SERPINC1)
| Target | Antithrombin-III (SERPINC1) |
| Clonality | Monoclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/100 - 1/1600. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 50-79 amino acids from human SERPINC1. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P01008 (UniProt, ExPASy) |
| UniProt Entry Name | ANT3_HUMAN |
| KEGG | hsa:462 |
| String | 9606.ENSP00000356671 |
| Molecular Weight | Calculated MW: 52.6 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |