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Protein SET (SET) Antibody
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Catalogue No: abx004747
Price:
US$203.00
(Size: 20 µl)
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SET Antibody is a Rabbit Polyclonal antibody against SET. The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.
Research Articles on Protein SET (SET)
| Target | Protein SET (SET) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human SET/TAF1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q01105 (UniProt, ExPASy) |
| UniProt Secondary AC | A5A5H4, A6NGV1, B4DUE2, Q15541, Q5VXV1, Q5VXV2, Q6FHZ5 |
| UniProt Entry Name | SET_HUMAN |
| Gene Symbol | SET |
| GeneID | 6418 |
| NCBI Accession | NP_003002.2 |
| KEGG | hsa:6418 |
| String | 9606.ENSP00000361777 |
| Molecular Weight | Calculated MW: 33 kDa Observed MW: 33 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |