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Histone-Lysine N-Methyltransferase SETMAR (SETMAR) Antibody
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Catalogue No: abx005169
Price:
US$203.00
(Size: 20 µl)
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SETMAR Antibody is a Rabbit Polyclonal antibody against SETMAR. This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Research Articles on Histone-Lysine N-Methyltransferase SETMAR (SETMAR)
| Target | Histone-Lysine N-Methyltransferase SETMAR (SETMAR) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | IHC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human SETMAR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q53H47 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DY74, E7EN68, Q13579, Q1G668, Q96F41 |
| UniProt Entry Name | SETMR_HUMAN |
| Gene Symbol | SETMAR |
| GeneID | 6419 |
| NCBI Accession | NP_006506.3 |
| KEGG | hsa:6419 |
| String | 9606.ENSP00000373354 |
| Molecular Weight | Calculated MW: 78 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |