Splicing Factor 3B Subunit 3 (SF3B3) Antibody

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Catalogue No: abx026966
Price: US$326.25
(Size: 80 µl)
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Splicing Factor 3B Subunit 3 (SF3B3) Antibody
Splicing Factor 3B Subunit 3 (SF3B3) Antibody

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Datasheet SDS
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF (II) 31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF (II) containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

Target Splicing Factor 3B Subunit 3 (SF3B3)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 1046-1074 amino acids from the C-terminal region of human SF3B3.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q15393 (UniProt, ExPASy)
UniProt Secondary AC Q6NTI8, Q96GC0, Q9BPY2, Q9UFX7, Q9UJ29
UniProt Entry Name SF3B3_HUMAN
KEGG hsa:23450
String 9606.ENSP00000305790
Molecular Weight Calculated MW: 136 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse and Cow SF3B3.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Splicing Factor 3B Subunit 3 (SF3B3)
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