Serine/arginine-Rich Splicing Factor 1 (SFRS1) Antibody

SFRS1 is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins.

Target	Serine/arginine-Rich Splicing Factor 1 (SFRS1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 11-38 amino acids from the N-terminal region of human SFRS1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q07955 (UniProt, ExPASy)
UniProt Secondary AC	B2R6Z7, D3DTZ3, Q13809
UniProt Entry Name	SRSF1_HUMAN
KEGG	hsa:6426
String	9606.ENSP00000258962
Molecular Weight	Calculated MW: 27.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Cow, Pig and Chicken SFRS1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Serine/arginine-Rich Splicing Factor 1 (SFRS1)

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