Splicing Factor, Arginine/serine-Rich 7 (SFRS7) Antibody

The protein encoded by this gene is a member of the serine/arginine (SR) rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene.

Target	Splicing Factor, Arginine/serine-Rich 7 (SFRS7)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 69-98 amino acids from the N-terminal region of human SFRS7.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16629 (UniProt, ExPASy)
UniProt Secondary AC	B4DLU6, G5E9M3, Q564D3
UniProt Entry Name	SRSF7_HUMAN
KEGG	hsa:6432
String	9606.ENSP00000325905
Molecular Weight	Calculated MW: 27.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Cow SRSF7.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Splicing Factor, Arginine/serine-Rich 7 (SFRS7)

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