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Rho Guanine Nucleotide Exchange Factor 26 / SGEF (ARHGEF26) Antibody
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Catalogue No: abx027344
Price:
US$290.00
(Size: 80 µl)
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SGEF/ARHGEF26 activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
Research Articles on Rho Guanine Nucleotide Exchange Factor 26 / SGEF (ARHGEF26)
| Target | Rho Guanine Nucleotide Exchange Factor 26 / SGEF (ARHGEF26) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 378-406 amino acids from the Central region of human SGEF. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96DR7 (UniProt, ExPASy) |
| UniProt Entry Name | ARHGQ_HUMAN |
| Gene Symbol | ARHGEF26 |
| GeneID | 26084 |
| OMIM | 617552 |
| HGNC | 24490 |
| KEGG | hsa:26084 |
| Ensembl | ENSG00000114790 |
| String | 9606.ENSP00000348828 |
| Molecular Weight | Calculated MW: 97.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |