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SH3 Domain Binding Protein 1 (SH3BP1) Antibody
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Catalogue No: abx029169
Price:
US$290.00
(Size: 80 µl)
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SH3BP1 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho-or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity).
Research Articles on SH3 Domain Binding Protein 1 (SH3BP1)
| Target | SH3 Domain Binding Protein 1 (SH3BP1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 419-446 amino acids from the Central region of human SH3BP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y3L3 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5R3N0, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9 |
| UniProt Entry Name | 3BP1_HUMAN |
| Gene Symbol | SH3BP1 |
| String | 9606.ENSP00000350018 |
| Molecular Weight | Calculated MW: 75.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat SH3BP1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |