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SH3 And Multiple Ankyrin Repeat Domains 2 (SHANK2) Antibody
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Catalogue No: abx027014
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq].
Research Articles on SH3 And Multiple Ankyrin Repeat Domains 2 (SHANK2)
| Target | SH3 And Multiple Ankyrin Repeat Domains 2 (SHANK2) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 879-908 amino acids from the Central region of human SHANK2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UPX8 (UniProt, ExPASy) |
| UniProt Secondary AC | C0SPG8, C0SPG9, Q3Y8G9, Q52LK2, Q9UKP1 |
| UniProt Entry Name | SHAN2_HUMAN |
| Gene Symbol | SHANK2 |
| String | 9606.ENSP00000469689 |
| Molecular Weight | Calculated MW: 159 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |