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E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) Antibody
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Catalogue No: abx028787
Price:
US$290.00
(Size: 80 µl)
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SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq].
Research Articles on E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1)
| Target | E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 92-120 amino acids from the Central region of human SIAH1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8IUQ4 (UniProt, ExPASy) |
| UniProt Secondary AC | A0FKF3, O43269, Q49A58, Q92880 |
| UniProt Entry Name | SIAH1_HUMAN |
| Gene Symbol | SIAH1 |
| KEGG | hsa:6477 |
| String | 9606.ENSP00000349156 |
| Molecular Weight | Calculated MW: 31.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |