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E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) Antibody
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Catalogue No: abx001938
Price:
US$203.00
(Size: 20 µl)
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SIAH1 Antibody is a Rabbit Polyclonal antibody against SIAH1. This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Research Articles on E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1)
| Target | E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human SIAH1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8IUQ4 (UniProt, ExPASy) |
| UniProt Secondary AC | A0FKF3, O43269, Q49A58, Q92880 |
| UniProt Entry Name | SIAH1_HUMAN |
| Gene Symbol | SIAH1 |
| GeneID | 6477 |
| NCBI Accession | NP_001006611.1 |
| KEGG | hsa:6477 |
| String | 9606.ENSP00000349156 |
| Molecular Weight | Calculated MW: 31 kDa Observed MW: 31 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |