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Sirtuin 2 (SIRT2) Antibody
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Catalogue No: abx000658
Price:
US$348.00
(Size: 60 µl)
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SIRT2 Antibody is a Rabbit Polyclonal antibody against SIRT2. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.
Research Articles on Sirtuin 2 (SIRT2)
| Target | Sirtuin 2 (SIRT2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200, IF/ICC: 1/10 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human SIRT2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8IXJ6 (UniProt, ExPASy) |
| UniProt Entry Name | SIR2_HUMAN |
| Gene Symbol | SIRT2 |
| GeneID | 22933 |
| NCBI Accession | NP_036369.2 |
| KEGG | hsa:22933 |
| String | 9606.ENSP00000249396 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
