Sirtuin 5 (SIRT5) Antibody

SIRT5 Antibody is a Rabbit Polyclonal antibody against SIRT5. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.

Target	Sirtuin 5 (SIRT5)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 37-310 of human SIRT5.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NXA8 (UniProt, ExPASy)
UniProt Secondary AC	B4DFM4, B4DYJ5, F5H5Z9, Q5T294, Q5T295, Q9Y6E6
UniProt Entry Name	SIR5_HUMAN
Gene Symbol	SIRT5
GeneID	23408
NCBI Accession	NP_036373.1
String	9606.ENSP00000476228
Molecular Weight	Calculated MW: 34 kDa Observed MW: 35 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Sirtuin 5 (SIRT5)

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