Solute Carrier Family 22 Member 5 (SLC22A5) Antibody

SLC22A5 Antibody is a Rabbit Polyclonal antibody against SLC22A5. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. [provided by RefSeq, Jul 2008].

Target	Solute Carrier Family 22 Member 5 (SLC22A5)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 430-529 of human SLC22A5.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O76082 (UniProt, ExPASy)
UniProt Secondary AC	A2Q0V1, B2R844, D3DQ87, Q6ZQZ8, Q96EH6
UniProt Entry Name	S22A5_HUMAN
Gene Symbol	SLC22A5
GeneID	6584
NCBI Accession	NP_003051.1
KEGG	hsa:6584
String	9606.ENSP00000245407
Molecular Weight	Calculated MW: 63 kDa Observed MW: 70 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Solute Carrier Family 22 Member 5 (SLC22A5)

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