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Mothers Against Decapentaplegic Homolog 4 (SMAD4) Antibody
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Catalogue No: abx033660
Price:
US$326.25
(Size: 80 µl)
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SMAD4 is the common SMAD (co-SMAD) mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
Research Articles on Mothers Against Decapentaplegic Homolog 4 (SMAD4)
| Target | Mothers Against Decapentaplegic Homolog 4 (SMAD4) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 400-428 amino acids from the C-terminal region of human SMAD4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13485 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K405 |
| UniProt Entry Name | SMAD4_HUMAN |
| KEGG | hsa:4089 |
| String | 9606.ENSP00000341551 |
| Molecular Weight | Calculated MW: 60.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Pig SMAD4. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |