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Mothers Against Decapentaplegic Homolog 6 (SMAD6) Antibody
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Catalogue No: abx000769
Price:
US$203.00
(Size: 20 µl)
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SMAD6 Antibody is a Rabbit Polyclonal antibody against SMAD6. The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on Mothers Against Decapentaplegic Homolog 6 (SMAD6)
| Target | Mothers Against Decapentaplegic Homolog 6 (SMAD6) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 257-496 of human Smad6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O43541 (UniProt, ExPASy) |
| UniProt Secondary AC | A9J6M5, O43654, Q15799, Q7Z7L4, Q96E31, Q9UKZ3 |
| UniProt Entry Name | SMAD6_HUMAN |
| Gene Symbol | SMAD6 |
| GeneID | 4091 |
| NCBI Accession | NP_005576.3 |
| KEGG | hsa:4091 |
| String | 9606.ENSP00000288840 |
| Molecular Weight | Calculated MW: 53 kDa Observed MW: 48 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |