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SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator of Chromatin Subfamily E Member 1 (SMARCE1) Antibody
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Catalogue No: abx004102
Price:
US$203.00
(Size: 20 µl)
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SMARCE1 Antibody is a Rabbit Polyclonal antibody against SMARCE1. The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
Research Articles on SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator of Chromatin Subfamily E Member 1 (SMARCE1)
| Target | SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator of Chromatin Subfamily E Member 1 (SMARCE1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-411 of human BAF57/BAF57/SMARCE1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q969G3 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KMC1, B4DFR4, C0IMW4, C0IMW5, C0IMW7, H7C3F6, O43539 |
| UniProt Entry Name | SMCE1_HUMAN |
| Gene Symbol | SMARCE1 |
| GeneID | 6605 |
| OMIM | 603111 |
| NCBI Accession | NP_003070.3 |
| HGNC | 11109 |
| KEGG | hsa:6605 |
| Ensembl | ENSG00000073584 |
| String | 9606.ENSP00000323967 |
| Molecular Weight | Calculated MW: 47 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |