Sphingomyelin Phosphodiesterase (SMPD1) Antibody

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Catalogue No: abx005173
Price: US$217.50
(Size: 20 µl)
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Western blot analysis of various lysates using SMPD1 / ASM Antibody at 1/1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates / proteins: 25 µg per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
Sphingomyelin Phosphodiesterase (SMPD1) Antibody Sphingomyelin Phosphodiesterase (SMPD1) Antibody

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Datasheet SDS
SMPD1 Antibody is a Rabbit Polyclonal antibody against SMPD1. The protein encoded by this gene is a lysosomal Sphingomyelin Phosphodiesterase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.

Target Sphingomyelin Phosphodiesterase (SMPD1)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IF/ICC
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/100 - 1/500, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 70-340 of human SMPD1 / ASM.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P17405 (UniProt, ExPASy)
UniProt Secondary AC A8K8M3, E9PKS3, P17406, Q13811, Q16837, Q16841
UniProt Entry Name ASM_HUMAN
Gene Symbol SMPD1
GeneID 6609
OMIM 607608
NCBI Accession NP_000534.3
HGNC 11120
KEGG hsa:6609
Ensembl ENSG00000166311
String 9606.ENSP00000340409
Molecular Weight Calculated MW: 70 kDa
Observed MW: 55/70 kDa
Buffer PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Sphingomyelin Phosphodiesterase (SMPD1)
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