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Sphingomyelin Phosphodiesterase (SMPD1) Antibody
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Catalogue No: abx005173
Price:
US$203.00
(Size: 20 µl)
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SMPD1 Antibody is a Rabbit Polyclonal antibody against SMPD1. The protein encoded by this gene is a lysosomal Sphingomyelin Phosphodiesterase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
Research Articles on Sphingomyelin Phosphodiesterase (SMPD1)
| Target | Sphingomyelin Phosphodiesterase (SMPD1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 70-340 of human SMPD1 / ASM. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P17405 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K8M3, E9PKS3, P17406, Q13811, Q16837, Q16841 |
| UniProt Entry Name | ASM_HUMAN |
| Gene Symbol | SMPD1 |
| GeneID | 6609 |
| OMIM | 607608 |
| NCBI Accession | NP_000534.3 |
| HGNC | 11120 |
| KEGG | hsa:6609 |
| Ensembl | ENSG00000166311 |
| String | 9606.ENSP00000340409 |
| Molecular Weight | Calculated MW: 70 kDa Observed MW: 55/70 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |