Sphingomyelin Phosphodiesterase 3 (SMPD3) Antibody

SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.

Target	Sphingomyelin Phosphodiesterase 3 (SMPD3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 137-165 amino acids from the N-terminal region of human SMPD3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NY59 (UniProt, ExPASy)
UniProt Secondary AC	B7ZL82, Q2M1S8
UniProt Entry Name	NSMA2_HUMAN
Gene Symbol	SMPD3
String	9606.ENSP00000219334
Molecular Weight	Calculated MW: 71.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rat SMPD3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Sphingomyelin Phosphodiesterase 3 (SMPD3)

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