Small Nuclear Ribonucleoprotein U5 Subunit 200 (SNRNP200) Antibody

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Catalogue No: abx004666
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
SNRNP200 Antibody is a Rabbit Monoclonal antibody against SNRNP200. Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Target Small Nuclear Ribonucleoprotein U5 Subunit 200 (SNRNP200)
Clonality Monoclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1947-2136 of human SNRNP200.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O75643 (UniProt, ExPASy)
UniProt Secondary AC O94884, Q6NZY0, Q6PX59, Q8NBE6, Q96IF2, Q9H7S0
UniProt Entry Name U520_HUMAN
Gene Symbol SNRNP200
GeneID 23020
NCBI Accession NP_054733.2
KEGG hsa:23020
String 9606.ENSP00000317123
Molecular Weight Calculated MW: 245 kDa
Observed MW: 244 kDa
Buffer PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Small Nuclear Ribonucleoprotein U5 Subunit 200 (SNRNP200)


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