Suppressor of Cytokine Signaling 1 (SOCS-1) Antibody

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Catalogue No: abx218825
Price: US$406.00
(Size: 100 µg)
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WB analysis of mouse lung, using SOCS1 antibody (1/1000 dilution).
Suppressor of Cytokine Signaling 1 (SOCS-1) Antibody Suppressor of Cytokine Signaling 1 (SOCS-1) Antibody

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Suppressor of Cytokine Signaling 1 (SOCS-1) Antibody is a Rabbit Polyclonal antibody for the detection of SOCS1.

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN) -gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Target Suppressor of Cytokine Signaling 1 (SOCS-1)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Suppressor of cytokine signaling 1
Isotype IgG
Form Liquid
Purity ≥ 95% (SDS-PAGE)
Purification Purified by immunogen affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity 12 months.
UniProt Primary AC O15524 (UniProt, ExPASy)
UniProt Secondary AC O15097, Q9NSA7
UniProt Entry Name SOCS1_HUMAN
Gene Symbol SOCS1
GeneID 8651
OMIM 603597
HGNC 19383
KEGG hsa:8651
Ensembl ENSG00000185338
String 9606.ENSP00000329418
Molecular Weight Observed MW: 24 kDa
Buffer PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration 2 mg/ml
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Suppressor of Cytokine Signaling 1 (SOCS-1)
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