+44 (0) 1223 755950
+1 832 327 7413
Superoxide Dismutase [Mn], Mitochondrial (SOD2) Antibody
REQUEST MORE INFO
Catalogue No: abx117084
Price:
US$522.00
(Size: 100 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
![Superoxide Dismutase [Mn], Mitochondrial (SOD2) Antibody](https://www.abbexa.com/image/cache/catalog/Antibody_Box-500x500.png "Superoxide Dismutase [Mn], Mitochondrial (SOD2) Antibody")
SOD2 Antibody is a Rabbit Polyclonal antibody against SOD2. The superoxide dismutase family is composed of three metalloenzymes (SOD-1, SOD-2 and SOD-3) that catalyze the oxido-reduction of reactive oxygen species (ROS) such as superoxide anionThe SOD-2 precursor is a 222 amino acid protein that is encoded by nuclear chromatin, synthesized in the cytosol and imported posttranslationally into the mitochondrial matrixUnlike SOD-1, which is a homodimeric cytosolic Cu-Zn enzyme, SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrionROS are implicated in a wide range of degeneRative processes, including Alzheimer’s disease, Parkinson’s disease and ischemic heart diseaseHomozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiRatory chain deficiencies in heart and skeletal musclePolymorphisms in the SOD-2 gene have also been implicated in nonfamilial, idiopathic, dilated cardiomyopathy in humans.
Research Articles on Superoxide Dismutase [Mn], Mitochondrial (SOD2)
| Target | Superoxide Dismutase [Mn], Mitochondrial (SOD2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human SOD2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P04179 (UniProt, ExPASy) |
| Gene Symbol | SOD2 |
| GeneID | 6648 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |