Human soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) ELISA Kit

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Catalogue No: abx253226
Price: US$797.50
(Size: 96 tests)
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Human soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) ELISA Kit

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Datasheet SDS Download Manual
Human soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Soluble Triggering Receptor Expressed On Myeloid Cells 1 concentrations in serum, plasma and other biological fluids.

Introduction Triggering receptor expressed on myeloid cells 1 is a protein that in humans is encoded by the TREM1 gene. Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1), Fc receptors (see MIM 146790), CD14 and Toll-like receptors (e.g., TLR4), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1). In granulocyte cells, TREM1 is activated by C/EBPε independently from inflammatory response.
Target soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1)
Reactivity Human
Tested Applications ELISA
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Validity The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Stability The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.
UniProt Primary AC Q9NP99 (UniProt, ExPASy)
UniProt Entry Name TREM1_HUMAN
Gene Symbol TREM1
OMIM 605085
HGNC 17760
String 9606.ENSP00000244709
Test Range 1.56 pg/ml - 100 pg/ml
Sensitivity 0.94 pg/ml
Standard Form Lyophilized
Detection Method Colorimetric
Assay Type Sandwich
Assay Data Quantitative
Sample Type Serum, plasma and other biological fluids.
Availability Shipped within 5-7 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES.

The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.

Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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Research Articles on soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1)
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