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Transcription Factor SOX-2 (SOX2) Antibody
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Catalogue No: abx031506
Price:
US$326.25
(Size: 80 µl)
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The intronless gene for SOX2 encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.
Research Articles on Transcription Factor SOX-2 (SOX2)
| Target | Transcription Factor SOX-2 (SOX2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 89-119 amino acids from the N-terminal region of human SOX2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48431 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14537 |
| UniProt Entry Name | SOX2_HUMAN |
| NCBI Accession | NP_003097.1 |
| KEGG | hsa:6657 |
| String | 9606.ENSP00000323588 |
| Molecular Weight | Calculated MW: 34.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Sheep, Zebrafish and Xenopus SOX2. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |