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SPO11, Initiator of Meiotic Double Stranded Breaks (SPO11) Antibody
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Catalogue No: abx029655
Price:
US$290.00
(Size: 80 µl)
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Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.
Research Articles on SPO11, Initiator of Meiotic Double Stranded Breaks (SPO11)
| Target | SPO11, Initiator of Meiotic Double Stranded Breaks (SPO11) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 299-326 amino acids from the C-terminal region of human SPO11. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y5K1 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5TCI1, Q8N4V0, Q9NQM7, Q9NQM8 |
| UniProt Entry Name | SPO11_HUMAN |
| Gene Symbol | SPO11 |
| String | 9606.ENSP00000360310 |
| Molecular Weight | Calculated MW: 44.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |