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Serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) Antibody
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Catalogue No: abx005177
Price:
US$217.50
(Size: 20 µl)
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SPTLC1 Antibody is a Rabbit Polyclonal antibody against SPTLC1. This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.
Research Articles on Serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1)
| Target | Serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 37-310 of human SPTLC1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O15269 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K681, Q5VWB4, Q96IX6 |
| UniProt Entry Name | SPTC1_HUMAN |
| Gene Symbol | SPTLC1 |
| GeneID | 10558 |
| NCBI Accession | NP_006406.1 |
| KEGG | hsa:10558 |
| String | 9606.ENSP00000262554 |
| Molecular Weight | Calculated MW: 53 kDa Observed MW: 53 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |